The 8-in-1 BioSerum is DefenAge's iconic bestseller. The remarkably smart formula seems to understand your skin’s needs better than your own DNA. Designed to activate, orchestrate and energize, this biologically-advanced anti aging cream-like serum concentrate provides an unprecedented concentration of defensin molecules contained in the Age-Repair Defensin® Complex. Dermatologists and aesthetic professionals name defensins as a perfect retinol alternative and the 8-in-1 BioSerum as a retinol serum replacement. The best part? Results are equal to 8 separate serums. Apply with the 24/7 Barrier Balance Cream to create smoother, younger looking skin. Patent-pending technology. Get the best skin ever today!

• • Rejuvenates smoothness. Improves overall visible skin health and quality.

• • Minimizes the look of fine lines, wrinkles, pores, and skin pigmentation and discolorations.

• • Promotes radiance and revives the skin’s natural moisture for an ultimate glow.

• • Brightens the overall skin tone and clarity and enhances skin luminosity.

• • Renews the feeling of skin firmness, elasticity, and texture.

• • Helps improve the appearance of skin redness.

• • Promotes the skin barrier and immunity.

Why it’s different

• • Advanced targeted cosmetic treatment with an established and validated science. A unique mechanism of action.

• • Contains 5 times more defensin-molecules than any other formulas.

• • Light-weight application; “you don't feel it when you're wearing it”.

• • Effective and safe for the entire face, including the delicate skin around the eyes and lips, and the neck and décolleté. High-performing on the crepey thin skin on the neck and arms.

• • Fast acting anti-aging – first results are seen within a few weeks.

• • Perfect as a daily skincare product for both men and women.

• • Effective for both early and late stages of skin aging, including people above 70.

• • Non-irritating and gentle on sensitive skin overall, and over retinols.

• • Tolerated by all skin types. Good for rosacea and melasma patients, can be combined with other treatments for rosacea patients.

• • Highly effective for pre- and post- aesthetic procedures to achieve the optimal outcomes, including microneedling and fractional and resurfacing/ablative laser treatments. Primes the skin to a quick and robust response. Optimizes healing and minimizes the risk of acne break-outs post-procedure.

• • Effective to prep the skin and enhance filler results, recommended to use 4-6 weeks before a filler procedure.

• • DefenAge's most “likable” product with the most impressive consumer feedback.

• • Mega size, 1.5 fl oz, is now available.

Made in the U.S.A.